Home/ Shop/ Longevity/ MOTS-C 10 MG Peptide

Longevity

MOTS-C 10 MG Peptide

10MG · Mitochondrial-derived

≥99% purity by HPLC
Janoshik COA with every lot
Lot-traceable from synthesis
EU-synthesised

In stock · Lot NZM-L-0017 · ships in 3–5 working days (EU)

Available for research procurement. Supplied as a lyophilized research compound with lot-specific COA.

Specifications

Lot NumberNZM-L-0017

Purity99.4% (HPLC)

Verified byJanoshik

Synthesis Date2026-04-10

FormLyophilized powder

StorageBelow 16°C · sealed

Third Party Lab Tested

Every lot is independently HPLC-tested by Janoshik Analytical, Europe's reference laboratory for peptide purity assessment. The COA shipped with your order is theirs, not ours.

Storage & Handling

Lyophilized peptides should be stored below 16°C, protected from light and moisture, for up to 24 months. Once reconstituted, refrigerate and use within 30 days for protocol consistency.

FormLyophilized powder

StorageLyophilized: below 16°C for up to 24 months. Reconstituted: refrigerate, use within 30 days.

Reconstitution

Reconstitute with bacteriostatic water using the volumes below. Add solvent slowly along the inside wall of the vial. Swirl gently, never shake, until fully dissolved.

Lab-handling protocol BAC Water · 0.9% benzyl alcohol The reconstitution solvent referenced above. Add to order →

Researched Benefits

AMPK Activation Mitochondrial Mitochondrially-encoded peptide modulating cellular energy. Insulin Sensitivity Improved Glucose homeostasis in metabolic-aging models.

Product details

Mitochondrial-to-nuclear signalling.

MOTS-C is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA region. Unlike peptides encoded by nuclear DNA, MOTS-C is studied as part of mitochondrial-to-nuclear communication and in experimental models involving AMPK signalling, cellular metabolism and stress adaptation.

This 10 MG MOTS-C peptide is supplied as a lyophilized research vial within the NZM-Labs research peptide range. Every production lot is independently analysed by HPLC and mass spectrometry, with lot-specific documentation available for matching the vial to its analytical record. For laboratory research only.

Compound Specs

Research specification table for MOTS-C 10 MG Peptide
Compound	MOTS-C
Sequence length	16 amino acids
Molecular mass	2174.6 Da
Mechanism / research class	Mitochondrial-derived peptide
Example laboratory preparation	10 MG vial with 2 mL bacteriostatic water (0.9% benzyl alcohol)
Calculated concentration	5 mg per 1.0 mL
Supply format	MOTS-C · 10 MG lyophilized research vial
Storage, lyophilized	store below 16°C for up to 24 months
Storage, reconstituted	refrigerate and use within 30 days

Quality standards

Synthesised.
Verified.
Documented.

Wireframe rendering of a research peptide vial alongside molecular structure

Verified Purity

Every lot HPLC-tested by Janoshik Analytical. Independent verification, never in-house only. Current lot: 99.4% (HPLC).

Mass-Spec Confirmed

Identity confirmed by mass spectrometry. Theoretical mass matches measured within 0.5 Da tolerance.

Lyophilized & Sealed

Supplied as lyophilized powder in a sealed crimp-cap vial for laboratory handling and storage.

Lot-Traceable

From synthesis batch to your delivery, every step is logged. Search lot NZM-L-0017 for full traceability.

Evidence base

Backed by research.
Measured in results.

Each tag opens the cited literature behind that effect. References are linked to PubMed.

Mitochondrial

AMPK Activation

MOTS-c is one of the first identified mitochondrially-derived peptides (MDPs). It activates AMPK and modulates downstream metabolic-flexibility endpoints in research models - uniquely encoded inside mitochondrial DNA itself rather than the nuclear genome.

References

Lee C et al. The mitochondrial-derived peptide MOTS-c regulates metabolic homeostasis. Cell Metab. 2015;21(3):443-454. PubMed ↗

Improved

Insulin Sensitivity

Exogenous MOTS-c administration produces measurable improvements in insulin sensitivity and glucose homeostasis markers in animal models of metabolic aging.

References

Reynolds JC et al. MOTS-c is an exercise-induced mitochondrial-encoded regulator. Nat Commun. 2021;12:470. PubMed ↗

Specific to MOTS-C 10 MG Peptide

Questions?
We have answers.

(01)

Why is a mitochondrially-encoded peptide unusual?

Most signaling peptides are encoded by the nuclear genome. MOTS-c is encoded inside mitochondrial DNA itself, which means the mitochondrion can signal its own metabolic state to the rest of the cell directly. That bidirectional communication is the research interest.

(02)

How is the Certificate of Analysis verified?

Every lot is sent to Janoshik Analytical for independent HPLC and mass spectrometry testing. The COA you receive is theirs, not ours - searchable by lot number on our Science page, no account required.

(03)

How is the product shipped?

Lyophilized vials are shipped across the EU. Store sealed vials below 16°C after delivery. Typical delivery takes 3–5 working days.

(04)

Is this a research product?

Yes. NZM peptides are sold strictly for in vitro and animal research use only. They are not for human consumption, off-label use, or clinical application. Please consult applicable local regulations before ordering.

(05)

What is the MOTS-c research peptide price?

The current MOTS-c price is shown on this page. Pricing applies to B2B research procurement only and may vary by lot, format, and availability.

(06)

Can research customers buy MOTS-c from NZM-Labs?

Yes. Research customers can order MOTS-c through NZM-Labs for in vitro and animal research use only. It is not sold for human consumption, clinical use, or self-administration.

Researcher reviews