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Cognitive

SEMAX

Nootropic · 10MG
32,00 
Size
Quantity
32,00 
1 - 2 vials
28,80  (10% off)
3 - 4 vials
27,20  (15% off)
5+ vials
x
  • ≥99% purity by HPLC
  • Janoshik COA with every lot
  • Lot-traceable from synthesis
  • EU-synthesised
In stock · Lot NZM-C-0012 · ships in 3–5 working days (EU)
Available for research procurement. Supplied as a lyophilized research compound with lot-specific COA.
Specifications
Lot NumberNZM-C-0012
Purity99.6% (HPLC)
Verified byJanoshik Analytical
Synthesis Date2026-04-02
FormLyophilized powder
StorageBelow 16°C · sealed
Third Party Lab Tested

Every lot is independently HPLC-tested by Janoshik Analytical, Europe's reference laboratory for peptide purity assessment. The COA shipped with your order is theirs, not ours.

Storage & Handling

Lyophilized peptides should be stored below 16°C, protected from light and moisture, for up to 24 months. Once reconstituted, refrigerate and use within 30 days for protocol consistency.

FormLyophilized powder
StorageLyophilized: below 16°C for up to 24 months. Reconstituted: refrigerate, use within 30 days.
Reconstitution

Reconstitute with bacteriostatic water using the volumes below. Add solvent slowly along the inside wall of the vial. Swirl gently, never shake, until fully dissolved.

Recommended2mL bacteriostatic water for injection (BWI). Yields 0.5mg per 0.1mL. Intranasal-stable.
SolventBacteriostatic water (0.9% benzyl alcohol)
MethodSlow side-injection · gentle swirl
After mixingRefrigerate · use within 30 days
Lab-handling protocol BAC Water · 0.9% benzyl alcohol The reconstitution solvent referenced above. Add to order →
Researched Benefits
BDNF Expression Upregulated Neurotrophic-factor modulation in cognitive-research models. Cognitive Stress Response Documented Animal-model research on memory and stress endpoints.
Product details

The ACTH-derived
nootropic.

Semax is a heptapeptide derived from the (4-10) fragment of adrenocorticotropic hormone (ACTH), with a stabilizing C-terminal tripeptide. Its research profile centers on BDNF expression, dopamine and serotonin modulation, and cognitive-stress response in animal models.

Originally developed in Russian research institutes, it has the deepest citation history of any peptide nootropic. For protocols studying neurotrophic-factor modulation specifically, it is the canonical reference.

Compound Specs
Research specification table for SEMAX
CompoundSemax
Molecular mass813.9 Da
Mechanism / research classHeptapeptide. Sequence: Met-Glu-His-Phe-Pro-Gly-Pro. ACTH (4-10) analog.
Lab handling solvent2mL bacteriostatic water for injection (BWI)
Resulting concentrationYields 0.5mg per 0.1mL. Intranasal-stable
Supply formatNootropic · 10MG lyophilized research vial
Storage, lyophilizedstore below 16°C for up to 24 months
Storage, reconstitutedrefrigerate and use within 30 days
Quality standards

Synthesised.
Verified.
Documented.

Wireframe rendering of a research peptide vial alongside molecular structure
01
Verified Purity
Every lot HPLC-tested by Janoshik Analytical. Independent verification, never in-house only. Current lot: 99.6% (HPLC).
02
Mass-Spec Confirmed
Identity confirmed by mass spectrometry. Theoretical mass matches measured within 0.5 Da tolerance.
03
Lyophilized & Sealed
Vacuum-dried under inert gas, sealed crimp-cap. Maximum stability until reconstitution. No heat exposure during shipping.
04
Lot-Traceable
From synthesis batch to your delivery, every step is logged. Search lot NZM-C-0012 for full traceability.
Evidence base

Backed by research.
Measured in results.

Each tag opens the cited literature behind that effect. References are linked to PubMed.

Upregulated
BDNF Expression

Semax research focuses on BDNF (brain-derived neurotrophic factor) expression upregulation, with downstream effects on dopamine and serotonin pathway modulation. The most-cited peptide nootropic in published Russian-origin research literature.

References
  1. Dolotov OV et al. Semax and BDNF expression. Neurochem Res. 2006;31(5):679-686. PubMed ↗
Documented
Cognitive Stress Response

Animal-model research literature documents effects on memory consolidation, attention, and stress-response endpoints - supporting Semax's role as a research reference for neurotrophic-pathway protocols.

References
  1. Eremin KO et al. Semax in cognitive stress models. Pharmacol Res. 2005;52(3):210-215. PubMed ↗
Specific to SEMAX

Questions?
We got answers.

(01)
Semax vs Selank - when to use which?
Both are short Russian-origin peptide nootropics, but the pathways differ: Semax modulates BDNF and dopamine/serotonin; Selank modulates GABAergic and serotonergic tone with anxiolytic effects in research models. Use Semax for neurotrophic studies, Selank for anxiety / stress-response studies.
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(02)
How is the Certificate of Analysis verified?
Every lot is sent to Janoshik Analytical for independent HPLC and mass spectrometry testing. The COA you receive is theirs, not ours - searchable by lot number at coa.nzmlab.com with no account required.
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(03)
How is the product shipped?
Lyophilized vials are shipped temperature-controlled across the EU and UK. Store sealed vials below 16°C after delivery; normal 3–5 working day transit has no measurable impact on potency.
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(04)
Is this a research product?
Yes. NZM peptides are sold strictly for in vitro and animal research use only. They are not for human consumption, off-label use, or clinical application. Please consult applicable local regulations before ordering.
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(05)
What is the Semax research peptide price?
The current Semax price is shown on this page. Pricing applies to B2B research procurement only and may vary by lot, format, and availability.
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(06)
Can research customers buy Semax from NZM-Labs?
Yes. Research customers can order Semax through NZM-Labs for in vitro and animal research use only. It is not sold for human consumption, clinical use, or self-administration.
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Researcher notes
Show references

Used in published research.

SEMAX

Ordered SEMAX for a research-protocol pilot. Arrived in 4 days temperature-controlled, vials sealed and properly lyophilized. Reconstituted cleanly in BWI with no haze. Will reorder.

R. Holm
University Lab Tech · Copenhagen
Researcher reviews

4.8 / 5

Based on 9 verified researcher reviews
28 MAR 2026

Solid product, fast EU shipping

Ordered SEMAX for a research-protocol pilot. Arrived in 4 days temperature-controlled, vials sealed and properly lyophilized. Reconstituted cleanly in BWI with no haze. Will reorder.

R. Holm
University Lab Tech · Copenhagen
EU Tested
COA per Lot
Research Use Only